Hello and welcome to this week’s edition of HealthBeat, Chiropractic OnLine Today’s Health, News and Informational Podcast.
In this week’s news: We’ll Be Looking At –
- Lumbar MRI Error Rates
- And Finally, a Story about Resolution of Inflammation
For HealthBeat …. This is Dr. Todd Eglow!
Welcome to HealthBeat Podcast #575 recorded December 16, 2016.
HealthBeat is Chiropractic OnLine Today’s radio program, providing current news and commentary about Chiropractic and Health.
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And Now for some news ….
Lumbar MRI Error Rates
A study was published in the journal Spine, that tested the authors’ hypothesis that the radiologist’s reports from multiple imaging centers performing a lumbar MRI exam on the same patient over a short period of time will have (1) marked variability in interpretive findings and (2) a broad range of interpretive errors.
In today’s healthcare climate, Magnetic Resonance Imaging (MRI) is often perceived as a commodity – a service where there are no meaningful differences in quality and thus an area in which patients can be advised to select a provider based on price and convenience alone.
If this prevailing view is correct, then a patient should expect to receive the same radiological diagnosis regardless of which imaging center he or she visits or which radiologist reviews the examination. Based on their extensive clinical experience, the authors believe that this assumption is not correct and that it can negatively impact patient care, outcomes and costs.
This study’s conclusion found marked variability in the reported interpretive findings and a high prevalence of interpretive errors in the radiologists’ reports of an MRI exam of the lumbar spine performed on the same patient at 10 different MRI centers over a short time period.
As a result, the authors’ conclude that where a patient obtains their MRI exam and which radiologist interprets the exam may have a direct impact on their radiologic diagnosis, subsequent choice of treatment and clinical outcome.
Surf to our Show notes for Links – https://www.ncbi.nlm.nih.gov/m/pubmed/27867079/
Resolution of Inflammation
Acute inflammation normally resolves by mechanisms that have remained somewhat elusive.
A 2005 Study published in the journal Nature Immunology, proposes that emerging evidence now suggests that an active, coordinated program of resolution initiates in the first few hours after an inflammatory response begins.
After entering tissues, granulocytes promote the switch of arachidonic acid-derived prostaglandins and leukotrienes to lipoxins, which initiate the termination sequence. Neutrophil recruitment thus ceases and programmed death by apoptosis is engaged.
These events coincide with the biosynthesis, from omega-3 polyunsaturated fatty acids, of resolvins and protectins, which critically shorten the period of neutrophil infiltration by initiating apoptosis.
Consequently, apoptotic neutrophils undergo phagocytosis by macrophages, leading to neutrophil clearance and release of anti-inflammatory and reparative cytokines such as transforming growth factor-beta1.
The anti-inflammatory program ends with the departure of macrophages through the lymphatics.
Understanding these and further details of the mechanism required for inflammation resolution may underpin the development of drugs that can resolve inflammatory processes in directed and controlled ways.
Surf to our Show Notes for Links – http://www.nature.com/ni/journal/v6/n12/full/ni1276.html
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– Brian Tracy
For Chiropractic OnLine Today’s HealthBeat, This has been
Dr. Todd Eglow.