Hello and welcome to this week’s edition of HealthBeat, Chiropractic OnLine Today’s Health, News and Informational Podcast.
In this week’s news: We’ll Be Looking At –
- Glutamate receptors and pain
- And Finally, a story about Chronic Back Pain and Abnormal Brain Chemistry
For HealthBeat, wishing everyone a Safe, Healthy and Happy Holiday Season …. This is Dr. Todd Eglow!
Welcome to HealthBeat Podcast #576 recorded December 23, 2016.
HealthBeat is Chiropractic OnLine Today’s radio program, providing current news and commentary about Chiropractic and Health.
You can download this week’s Podcast here – http://www.chiropracticradio.com/healthbeat/healthbeat0576.mp3
COT’s HealthBeat is now available on demand on Stitcher Radio – http://app.stitcher.com/browse/feed/31530/details
We also would appreciate your passing the word of our Podcasts to your friends and colleagues. Please let everyone know how easy it is to subscribe via the Apple iTunes directory.
If you are interested in creating personalized Healthbeat podcasts for your office or website, to help attract new patients, please surf to our web site and send us an Email ….
…. or Skype us by typing in “healthbeat”, all in small letters.
Twitter – We are always looking to expand our interactivity with you, our loyal Health Community. If you would like to be kept up-to-date with current events about Health, Technology and ME, feel free to surf to – http://www.twitter.com/teglow and click on the Follow link.
Next, we would like to send out a big Thank You to those of you who are linking our Podcast to your home pages…. We do request that you also include a link to our main Podcast Page at www.ChiropracticRadio.com
And as always, a big thank you to our COT HealthBeat Listener community. This podcast is made available thru the generous donations we receive and greatly appreciate. If you could remember to surf to our Web Site and click on the PayPal link to make a monthly donation, even $5-$10, this would be very much welcomed.
Finally, Chiropractic OnLine Today has always provided our news and education content for free and plan on continuing this policy. However, we do request that if you are enjoying these podcasts, that you surf to ChiropracticRadio.com and consider clicking on our PayPal link to make a donation to keep these Podcasts airing. We thank everyone for their continued support.
And Now for some news ….
Glutamate receptors and pain
A 2006 study published in the journal Seminars in Cell & Developmental Biology, looked at the connection between the neurotransmitter Glutamate Receptors and Pain.
Pain is an important survival and protection mechanism for animals. However, chronic/persistent pain may be differentiated from normal physiological pain in that it confers no obvious advantage.
An accumulating body of pharmacological, electrophysiological, and behavioral evidence is emerging in support of the notion that glutamate receptors play a crucial role in pain pathways and that modulation of glutamate receptors may have potential for therapeutic utility in several categories of persistent pain, including neuropathic pain resulting from injury and/or disease of central (e.g., spinal cord injury) or peripheral nerves (e.g., diabetic neuropathy, radiculopathy) and inflammatory or joint-related pain (e.g., rheumatoid arthritis, osteoarthritis).
This review focuses on the role of glutamate receptors, including both ionotropic and metabotropic receptors in persistent pain states with particular emphasis on their expression patterns in nociceptive pathways and their potential as targets for pharmacological intervention strategies.
Surf to our Show Notes for Links – http://www.sciencedirect.com/science/article/pii/S1084952106001121
Chronic Back Pain and Abnormal Brain Chemistry
A 2000 study published in the journal Pain, looked at the relationship between Chronic Back Pain and Abnormal Brain Chemistry.
The neurobiology of chronic pain, including chronic back pain, is unknown.
Structural imaging studies of the spine cannot explain all cases of chronic back pain. Functional brain imaging studies indicate that the brain activation patterns are different between chronic pain patients and normal subjects, and the thalamus, and prefrontal and cingulate cortices are involved in some types of chronic pain.
Animal models of chronic pain suggest abnormal spinal cord chemistry.
The authors of the study used MRI to measure relative concentrations of N-acetyl aspartate, creatine, choline, glutamate, glutamine, gamma-aminobutyric acid, inositol, glucose and lactate in relation to the concentration of creatine.
The results of the study show that chronic back pain alters the human brain chemistry.
Reductions of N-acetyl aspartate and glucose were demonstrated in the dorsolateral prefrontal cortex. Cingulate, sensorimotor, and other brain regions showed no chemical concentration differences.
In chronic back pain, the interrelationship between chemicals within and across brain regions was abnormal, and there was a specific relationship between regional chemicals and perceptual measures of pain and anxiety.
These findings provide direct evidence of abnormal brain chemistry in chronic back pain, which may be useful in diagnosis and future development of more effective pharmacological treatments.
Surf to our Show Notes for links – https://www.ncbi.nlm.nih.gov/pubmed/11113288
This podcast is made available through the generous donations from our great Listeners, such as You! If you are enjoying these HealthBeat Podcasts, Please surf to our Web Site and click on the PayPal link.
For information about adding Personalized HealthBeat Podcasts to your office’s Web Site, to help you attract new patients, please Email us at – email@example.com
And remember to surf to our Show Notes, located at http://www.ChiropracticRadio.com
As always, please surf to our Podcast Show Notes at ChiropracticRadio.com for a full listing of web references mentioned in today’s show.
And remember – COT’s Healthbeat always recommends discussing any nutritional or exercise lifestyle modifications with a qualified healthcare professional.
Thank you for listening…. As always, We Want to hear from you. Please send us emails…. Simply surf to our Web Site at ChiropracticRadio.com and click on the Email link.
You can also leave us Voice Mail…. Simply open up your Skype and type in “healthbeat”, all in small letters.
If you have an idea for a future Health Segment, please feel free to contact me directly via email …. The address is: firstname.lastname@example.org
We also would appreciate your votes both at Podcastalley.com. If you are enjoying these podcasts, please surf to our HealthBeat homepage and click on the Podcast Alley link and Yahoo links.
If you have a Web Site for your practice and you would like to add content to help attract more patients, please consider adding a Personalized HealthBeat segments to your site. Many listeners are finding this a useful content addition to an Office’s Web Site. For more information, please send me an Email at email@example.com
While at our Web Site, please remember to consider making a donation to help keep these Podcasts airing. Listener support such as yours, via our PayPal link, does help in allowing us to bring these Podcasts to you weekly.
And please remember to support our sponsors by clicking their links located at ChiropracticRadio.com
Finally, I leave you with the following quote:
“We Generate Fears While We Sit. We Overcome Them By Action.”
– Dr. Henry Link
For Chiropractic OnLine Today’s HealthBeat, This has been
Dr. Todd Eglow.