A recent study showed that chiropractic patients had fewer days with bothersome (activity-limiting) low back pain (LBP) when receiving care at regular pre-planned intervals regardless of symptoms (‘maintenance care’, MC) compared to receiving treatment only with a new episode of LBP.
Monthly Archives: April 2020
Hello and welcome to this week’s edition of HealthBeat, Chiropractic OnLine Today’s Health, News and Informational Podcast.
In this week’s news: We’ll Be Looking At –
- Non-Specific LBP and Inflammatory Profiles
- And Finally, a Story about SMT and Inflammatory Bio-Markers
For HealthBeat …. This is Dr. Todd Eglow!
Welcome to HealthBeat Podcast #709 recorded April 24, 2020
HealthBeat is Chiropractic OnLine Today’s radio program, providing current news and commentary about Chiropractic and Health.
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Non-Specific LBP and Inflammatory Profiles
The pathogenesis of low back pain (LBP) remains unclear. However, recent studies suggest that the inflammatory response may be inherent in spinal pain.
The purpose of a recent study, published in the Clinical Journal of Pain, was to discern inflammatory profiles in patients with nonspecific acute and chronic LBP in relation to those in asymptomatic individuals.
The levels of in vitro production of proinflammatory (tumor necrosis factor α [TNFα], interleukin [IL] 1β, IL-6, IL-2, interferon γ) and anti-inflammatory (IL-1 receptor antagonist, soluble receptors of TNF2, and IL-10) mediators were determined by specific immunoassays.
The study concluded that inflammatory profiles of patients with acute and chronic LBP are distinct. Nonetheless, in both patient groups, an imbalance between proinflammatory and anti-inflammatory mediator levels favors the production of proinflammatory components.
Surf to our Show Notes for Links – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735949/
SMT and Inflammatory Bio-Markers
The involvement of inflammatory components in the pathophysiology of low back pain (LBP) is poorly understood. It has been suggested that spinal manipulative therapy (SMT) may exert anti-inflammatory effects.
The purpose of a recent study published in the Clinical Journal of Pain, was to determine the involvement of inflammation-associated chemokines (CC series) in the pathogenesis of nonspecific LBP and to evaluate the effect of SMT on that process.
The in vitro levels of CC chemokine ligands (CCL2, CCL3, and CCL4) production and plasma levels of an inflammatory biomarker, soluble E-selectin (sE-selectin), were determined at baseline and at the termination of treatments 2 weeks later.
The study concluded that the production of chemotactic cytokines is significantly and protractedly elevated in LBP patients. Changes in chemokine production levels, which might be related to SMT, differ in the acute and chronic LBP patient cohorts.
Surf to our Show Notes for Links – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728592/
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For Chiropractic OnLine Today’s HealthBeat, Wishing everyone to stay Safe and Healthy, This has been Dr. Todd Eglow.